The January 19th issue of biobytes brings you highlights of the 2008 annual meeting of the American Society for Cell Biology. We learn how bone marrow transplants might stall neurodegeneration (Craig Montell, Johns Hopkins University Medical School, Baltimore, MD). JCB News Editor, Ben Short, tells us about David Boettiger's (University of Pennsylvania, PA) work on the extracellular matrix and cell signaling. We hear how cancer cells find their way into the brain (Joan Massagué, Memorial Sloan-Kettering Cancer Center, New York, NY). And lastly, we learn that fly phagocytes get the midnight munchies for certain bugs (Mimi Shirasu-Hiza, Stanford University, CA) and that breast cancer cells can have very intimate living arrangements (Michael Overholtzer, Memorial Sloan-Kettering Cancer Center, New York, NY). The show was written, presented and produced by Ruth Williams, with additional writing by Ben Short.